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Document Details
Document Type
:
Article In Journal
Document Title
:
Genomic Encyclopedia of Bacteria and Archaea: Sequencing a Myriad of Type Strains
Genomic Encyclopedia of Bacteria and Archaea: Sequencing a Myriad of Type Strains
Document Language
:
English
Abstract
:
Microbes hold the key to life. They hold the secrets to our past (as the descendants of the earliest forms of life) and the prospects for our future (as we mine their genes for solutions to some of the planet's most pressing problems, from global warming to antibiotic resistance). However, the piecemeal approach that has defined efforts to study microbial genetic diversity for over 20 years and in over 30,000 genome projects risks squandering that promise. These efforts have covered less than 20% of the diversity of the cultured archaeal and bacterial species, which represent just 15% of the overall known prokaryotic diversity. Here we call for the funding of a systematic effort to produce a comprehensive genomic catalog of all cultured Bacteria and Archaea by sequencing, where available, the type strain of each species with a validly published name (currently, 11,000). This effort will provide an unprecedented level of coverage of our planet's genetic diversity, allow for the large-scale discovery of novel genes and functions, and lead to an improved understanding of microbial evolution and function in the environment.
ISSN
:
1545-7885
Journal Name
:
PLOS BIOLOGY
Volume
:
12
Issue Number
:
8
Publishing Year
:
1435 AH
2014 AD
Article Type
:
Article
Added Date
:
Wednesday, August 2, 2017
Researchers
Researcher Name (Arabic)
Researcher Name (English)
Researcher Type
Dr Grade
Email
Nikos Kyrpides
Kyrpides, Nikos
Researcher
Philip Hugenholtz
Hugenholtz, Philip
Researcher
Jonathan Eisen
Eisen, Jonathan
Researcher
Tanja Woyke
Woyke, Tanja
Researcher
Markus ,.Goeker et al
,.Goeker et al, Markus
Researcher
Files
File Name
Type
Description
42418.pdf
pdf
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