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Faculty of Sciences
Document Details
Document Type
:
Article In Journal
Document Title
:
The Genetic Effect of the Combined Action of Vincristine and Fennel Plant Extract on the Germ Cells of Drosophilla melanogaster
التأثير الطفري للمعاملة المفردة والمشتركة لمستخلص نبات شمر وعقار الفينكريستين في حشرة الدروسوفيلا ميلانوجاستر
Subject
:
Biological
Document Language
:
English
Abstract
:
This study was designed to investigate the mutagenic potentiality of the anticancer drug vincristine and fennel plant extract on Drosophilla melanogaster using two test systems, the sex linked recessive lethal (SLRL) and estimating the activity of cholinesterase enzyme (ChE) in F1 and F2 bar eye females and F2 wild types males. A wild type Strain Oregon-R (or-R) male flies of D. melanogaster were treated on a medium containing a concentration of one of individually of the two agents, followed by combined treatment in an alternative way of fennel extract followed by vincristin, then vincristin followed by fennel extract and finally the two agents together. The results showed no significant increase in the percentage of the S.L.R.L in all stages of spermatogenesis in all treatments. Meanwhile, vincristine and fennel plant extract showed a genotoxic effects in the three categories of the two generations of S.L.R.L, F1 females heterozygous F2 bar eye females and F2 wild type males on the genetic background of ChE in all treatments.
ISSN
:
1012-1319
Journal Name
:
Science Journal
Volume
:
20
Issue Number
:
1
Publishing Year
:
2008 AH
2008 AD
Article Type
:
Article
Added Date
:
Tuesday, February 2, 2010
Researchers
Researcher Name (Arabic)
Researcher Name (English)
Researcher Type
Dr Grade
Email
ندى حسن التواتي
Al-Twaty, Naseer H
Researcher
Doctorate
ntwaty@yahoo.com
إكرام صلاح الدين أحمد
Ahmed, E S
Researcher
Doctorate
سهام عبدالله كردي
Al-Kurdi, S A
Researcher
Doctorate
Files
File Name
Type
Description
25023.pdf
pdf
Abstract
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