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Document Details
Document Type
:
Article In Journal
Document Title
:
THE FORMATION OF OXYTETRACYCLINE IN A DATE MEDIUM BY MUTANTS OF STREPTOMYCES-RIMOSUS INDUCED BY CHEM
THE FORMATION OF OXYTETRACYCLINE IN A DATE MEDIUM BY MUTANTS OF STREPTOMYCES-RIMOSUS INDUCED BY CHEM
Document Language
:
Arabic
Abstract
:
Nitrosoguanidine (NTG), nitrous acid and hydrogen peroxide were employed to induce auxotrophic mutants in S. rimosus. An increase in exposure time to each mutagen and dose of some of these mutagens led to a decrease in survival percentage and an increase in the percentage of mutation. H2O2 gave the highest total survivors percentage. Four mutants out of 26 NTG mutants gave higher antibiotic titres than the initial organism, while the other mutants were either non-oxytetracycline producers or active ones but with antibiotic formation less than that of the initial organism. None of the 51 HNO2 or 17 H2O2 mutants produced antibiotic titres higher than the parent microorganism.
Journal Name
:
BIORESOURCE TECHNOLOGY
Volume
:
42
Issue Number
:
3
Publishing Year
:
1992 AH
Added Date
:
Saturday, June 14, 2008
Researchers
Researcher Name (Arabic)
Researcher Name (English)
Researcher Type
Dr Grade
Email
أحمد عمر بغلف
Researcher
نبيه باعشن
Researcher
أبو زيد
Researcher
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