تفاصيل الوثيقة

نوع الوثيقة : مقال في مجلة دورية 
عنوان الوثيقة :
Management of painful vaso-occlusive crisis of sickle cell anemia: Consensus opinion
Management of painful vaso-occlusive crisis of sickle cell anemia: Consensus opinion
 
الموضوع : أمراض الدم 
لغة الوثيقة : الانجليزية 
المستخلص : Sickle-cell disease (SCD) is a wide-spread inherited hemolytic anemia that is due to a point mutation, leading to the substitution of valine for glutamic acid, causing a spectrum of clinical manifestations in addition to hemolysis and anemia. Acute painful crisis is a common sequela that can cause significant morbidity and negatively impact the patient's quality of life. Remarkable improvements in the understanding of the pathogenesis of this clinical syndrome and the role of cell adhesion, inflammation, and coagulation in acute painful crisis have led to changes in the management of pain. Due to the endemic nature of SCD in various parts of the Middle East, a group of physicians and scientists from the United States and Middle East recently met to draw up a set of suggested guidelines for the management of acute painful crisis that are reflective of local and international experience. This review brings together a detailed etiology, the pathophysiology, and clinical presentation of SCD, including the differential diagnoses of pain associated with the disease, with evidence-based recommendations for pain management and the potential impact of low-molecular-weight heparin (LMWH), from the perspective of physicians and scientists with long-term experience in the management of a large number of patients with SCD 
ردمد : 1076-0296 
اسم الدورية : Clinical and Applied Thrombosis/Hemostasis 
المجلد : 16 
العدد : 4 
سنة النشر : 1431 هـ
2010 م 
نوع المقالة : مقالة مراجعة 
تاريخ الاضافة على الموقع : Thursday, August 11, 2011 

الباحثون

اسم الباحث (عربي)اسم الباحث (انجليزي)نوع الباحثالمرتبة العلميةالبريد الالكتروني
سعاد الجاعونيAl-Jaouni, Soad باحث مشاركدكتوراه 
محمد قاريQari, Mohammed باحث مشاركدكتوراه 

الملفات

اسم الملفالنوعالوصف
 30185.pdf pdf 

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